Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Patent
1993-08-12
1995-09-12
Rollins, John W.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
514 25, A61K 3578
Patent
active
054495164
ABSTRACT:
A process for extracting and isolating compounds from the Brazilian ginseng plant, particularly of the genus Pfaffia and most particularly Pfaffia paniculata, results in therapeutic compositions for treatment of sickle cell symptomatology. The extracted compositions are made by crushing the Brazilian ginseng roots, washing the crushed roots in hot alcohol, and then drying and grinding the roots into a powder. The powder is then treated using N-butanol and chromatography to extract the therapeutic compositions. Administration of a therapeutically-effective amount of the Brazilian ginseng compositions to subjects having sickle cell disease symptoms results in increased hemoglobin levels, inhibited red blood cell sickling and generally improved physical condition during the treatment.
REFERENCES:
patent: 5198225 (1993-03-01), Meghack et al.
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De Oliveira, et al, Chem. Abst. 96(8):57621q; 1980.
Takemoto et al., Chem. Abst. 99(7):50248b, 1983.
Chem. Abst. 188(23):189046s, 1984.
Nishimoto et al, Chem. Abst. 101(3) 20525q; 1984.
Instituto de Medicina Tropical de Sao Paulo
Rollins John W.
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