Branched synthetic peptide conjugate

Details Branched synthetic peptide conjugate Branched synthetic peptide conjugate

1994-06-09

1997-10-07

Russel, Jeffrey E.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

530327, 530328, 530329, 530330, 530332, 530345, 930290, C07K 400, C07K 702, C07K 1400

Patent

active

056749775

ABSTRACT:
The invention is a branched synthetic peptide conjugate which can be designed to bind to a target cell surface receptor, to penetrate into target cells, and to deliver a diagnostic probe or cytotoxic functionality to a desired site of action. The invention provides a relatively small molecule of flexible design having a branched structure for systematically incorporating a desired number of cytotoxic functions, peptide-based localization signals or diagnostic probes. The invention addresses problems associated with protein-based therapeutic or diagnostic agents.

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