Branch migration of nucleotides

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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536 231, C12Q 168, C07H 2102

Patent

active

059586818

ABSTRACT:
Procedures and compositions for forming and stabilizing non stable branch migrated oligo- and polydeoxynucleotides utilizing a displacer which is either single stranded or partially double stranded and hybridized to a linker strand. The displacer may contain one or more modified nucleotides.

REFERENCES:
patent: 4766062 (1988-08-01), Diamond et al.
patent: 5124246 (1992-06-01), Urdea et al.
Quartin et al, Biochemistry 28(22) : 8676-8682, 1989.

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