Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1996-10-11
2000-01-11
Caputa, Anthony C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C07K 1447
Patent
active
060137673
ABSTRACT:
A novel brain-specific adapter molecule, its gene, an antibody to it, and a method of utilizing the antibody are provided. This invention screened a normalized cDNA library using mRNA derived from the human cerebrum, isolated a gene encoding a novel factor, FC99 protein, involved in the signaling pathways in neurons of the brain, and clarified its base sequence as well as a protein encoded by the gene. The invention also isolated from a rat brain-derived cDNA library a gene encoding rat FC99 protein, and clarified its base sequence as well as a protein encoded by the gene. The invention further produced an antibody to the protein, and measured tyrosine kinase activity in a cell by use of the antibody.
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Caputa Anthony C.
Gucker Stephen
Sumitomo Electric Industries Ltd.
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