Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-08-11
2010-10-12
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S252020, C514S253010, C514S253130, C514S336000, C514S352000, C544S224000, C544S238000, C544S360000, C544S366000, C544S367000, C544S399000, C546S256000, C546S265000
Reexamination Certificate
active
07812025
ABSTRACT:
A compound represented by the formula (I) or a salt thereof; and an agent for protecting a brain
euronal cell or a therapeutic agent for sleep disorder comprising the compound or salt: wherein Z represents an oxygen or sulfur; R1represents an aryl or heterocyclic group which may be substituted, provided that R1is not a 3-ethyl-6-methoxy-2-methyl-5-naphthalen-1-yl group; R1arepresents a hydrogen atom, a hydrocarbon group which may be substituted, a hydroxyl group or the like; R2represents a piperidin-1,4-diyl or piperazin-1,4-diyl which may be substituted; R3represents a bivalent group which is formed by removing two hydrogen atoms from a benzene ring or 6-membered aromatic heterocyclic ring which may have a substituent, provided that R3is not a pyridazin-3,6-diyl; and R4represents a group which is formed by removing one hydrogen atom from a benzene ring or 5- to 6-membered heterocyclic ring which may be substituted, provided that the substituent on the heterocyclic ring is not a phenylethyl group which may be substituted when Z is sulfur.
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Kori Masakuni
Kouno Mitsunori
Matsumoto Takahiro
Hamre Schumann Mueller & Larson P.C.
Sackey Ebenezer
Takeda Pharmaceutical Company Limited
Wilson James O
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