Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1994-05-09
1997-10-14
Draper, Garnette D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530350, 514 2, A61K 3800, A61K 3803, C07K 1447
Patent
active
056772777
ABSTRACT:
The present invention provides a novel isolated and purified protein that is produced by brain endothelial cells, has a molecular weight of approximately 67 kDa of SDS-PAGE, with the protein being capable of stimulating proliferation of cerebral arteriole smooth muscle cells. Also provided are various methods of using this novel protein or the gene encoding this protein, including methods of treating various cerebrovascular diseases.
REFERENCES:
Lillieu et al Nature 317 632-634 (1985).
Cordon-Cardo et al Cell 66 173-184 (1991).
Ikedo et al Brain Res 649 260-264 (1994).
Alam Nargis A.
Alam Syed S.
Yatsu Frank M.
Adler Benjamin Aaron
Draper Garnette D.
Kemmerer Elizabeth C.
Research Development Foundation
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