Bradykinin receptor antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S235500, C514S235800, C514S252110, C514S253010, C514S253110, C514S318000, C514S330000, C514S603000, C544S060000, C544S121000, C544S124000, C544S129000, C544S160000, C544S360000, C544S364000, C546S193000, C546S194000, C546S225000, C546S226000, C564S086000

Reexamination Certificate

active

06958331

ABSTRACT:
The invention relates to sulfonyl amine derivatives of formula IAwherein R5A, X1, X2, R9and R10are as defined herein, which derivatives are useful as bradykinin B1receptor antagonists.

REFERENCES:
patent: 6100278 (2000-08-01), Ferrari et al.
patent: WO 97/25315 (1997-07-01), None
Marceau F, Hess JF, Bachvarov DR, “The B1 receptors for kinins”, Pharmacol Rev. Sep. 1998;50(3):357-86.
Streitwieser, A. and Heathcock, C.H., “Introduction to Organic Chemistry, 2nd Ed.”, Macmillan, New York, 1981, p. 515.

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