Bradykinin antagonists containing pentafluorophenylalanine

Details Bradykinin antagonists containing pentafluorophenylalanine Bradykinin antagonists containing pentafluorophenylalanine

1998-06-12

1999-08-10

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530314, 530328, 930 21, 930 23, A61K 3800, A61K 3808

Patent

active

059359323

ABSTRACT:
The present invention provides bradykin antagonists containing pentafluorophenylalanine which are therapeutically useful. Moreover, the present invention provides methods to antagonize bradykinin receptors in a mammal in need of such antagonism, comprising administering a bradykinin antagonist containing pentafluorophenylalanine. Also provided are methods to treat inflammation in a mammal in need of such inhibition, comprising administering a bradykinin antagonist containing pentafluorophenylalanine. Lastly, a method to treat cancer in a mammal in need of such inhibition, comprising administering a bradykinin antagonist containing pentafluorophenylalanine.

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