Bradykinin antagonist quinolines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514312, 514313, 514314, 5142282, 5142355, 514253, 514259, 514260, 544 62, 544128, 544363, 546171, 546178, 546153, 546157, C07D21502, C07D23974, A61K 3147, A61K 31505

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active

055631622

ABSTRACT:
This invention relates to new heterocyclic compounds and pharmaceutically acceptable salts thereof. More particularly, this invention relates to new heterocyclic compounds and salts thereof which display bradykinin antagonist activity, to processes for preparing these compounds, to a pharmaceutical composition comprising these compounds, and to methods of using same in the prevention and/or the treatment of bradykinin- or bradykinin analogue-mediated diseases such as allergy, inflammation, autoimmune disease, shock, pain, or the like, in human beings or in animals.

REFERENCES:
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patent: 4749406 (1988-06-01), Martin
patent: 5006534 (1991-04-01), Mohrs et al.
patent: 5202336 (1993-04-01), Mohrs et al.
patent: 5212182 (1993-05-01), Musser et al.
patent: 5294622 (1994-03-01), Dreikorn et al.
Chemical Abstracts, vol. 97, 1982, p. 278, AN-18948c.
Chemical Abstracts, vol. 90, 1979, p. 136, AN-34849g.

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