Boxazomycin A and B, new antibiotics containing benzoxazole nucl

Details Boxazomycin A and B, new antibiotics containing benzoxazole nucl Boxazomycin A and B, new antibiotics containing benzoxazole nucl

1986-02-03

1987-09-01

Brust, Joseph P.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

435119, 435826, 544298, A61K 3142, C07D26358

Patent

active

046909265

ABSTRACT:
The novel antibiotics boxazomycin A and B, which have the formula: ##STR1## wherein R is --CH.sub.2 OH for boxazomycin A; and R is --CH.sub.3 for boxazomycin B. These new antibiotics, which are produced by cultivating a novel strain of Pseudonocardia (ATCC 53205), inhibit growth of aerobic Gram-positive bacteria and anaerobes with enhanced activity observed in acidic medium.

REFERENCES:
patent: 3927023 (1975-12-01), Brown et al.

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