Boxazomycin A and B, new antibiotics containing benzoxazole nucl

Details Boxazomycin A and B, new antibiotics containing benzoxazole nucl Boxazomycin A and B, new antibiotics containing benzoxazole nucl

1986-07-25

1988-03-01

Brust, Joseph Paul

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

435119, 435253, 435822, C12P 1716, C12N 120

Patent

active

047286121

ABSTRACT:
The novel antibiotics boxazomycin A and B, which have the formula: ##STR1## wherein R is --CH.sub.2 OH for boxazomycin A; and R is --CH.sub.3 for boxazomycin B. These new antibiotics, which are produced by cultivating a novel strain of Pseudonocardia (ATCC 53205), inhibit growth of aerobic Gram-positive bacteria and anaerobes with enhanced activity observed in acidic medium.

REFERENCES:
patent: 2328025 (1943-08-01), Mead, Jr. et al.
patent: 4458016 (1984-07-01), Yamanaka et al.

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