Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2005-09-06
2005-09-06
Spector, Lorraine (Department: 1646)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C536S023500, C435S069100
Reexamination Certificate
active
06939950
ABSTRACT:
The invention relates to nucleic acid sequences encoding a bovine tumor necrosis factor receptor-I (TNF-RI). Also within the invention is a soluble bovine TNF-RI, which is a potent inhibitor of bovine tumor necrosis factor-α (TNF-α). The invention demonstrates that soluble bovine TNF-RI has therapeutic value as an inhibitor of TNF in cattle suffering from coliform mastitis or other inflammatory disease.
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Kehrli, Jr. Marcus E.
Lee Eun-Kyung
Mwangi Simon
Taylor Michael J.
Fish & Richardson P.C. P.A.
Iowa State University Research Foundation
O'Hara Eileen B.
Spector Lorraine
The United States of America as represented by the Department of
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