Bovine neospora isolates

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing

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4352581, C12N 110

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active

057076170

ABSTRACT:
The present invention provides isolated bovine Neospora cultures. The cultures are used to develop diagnostic assays for the detection of Neospora infections in cattle and other animals. Also provided are pharmaceutical compositions for the treatment and prevention of Neospora infections.

REFERENCES:
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Anderson et al. JAVMA 198(2):241-2 44 (1991).
Dubey et al., Journal of Parsitology 76(5):732-734 (1990).
Dubey et al., JAVMA 201(5):709-713 (1992).
Barr, B.C., et al. (1990) "Bovine Fetal Encephalitis and Myocarditis Associated With Protozoal Infections", Vet Pathol, 27:354-361.
Barr, Brad C., et al. (1991) "Neospora-like encephalomyelitis in a calf: pathology, ultrastructure, and immunoreactivity"J. Vet. Diagn. Invest, 3:39-46.
Dubey, J.P., et al. (1988) "Neonatal Neospora caninum infection in dogs: Isolation of the causative agent and experimental transmission", JAVMA, 193(10):1259-1263.
Anderson, Mark L., et al. (1991) "Neospora-like protozoan infection as a major cause of abortion in California dairy cattle", JAVMA, 198(2) :241-244.
Dubey, J.P. (1992) "A Review of Neospora caninum and Neospora-like Infections in Animals", J. Protozool. Res., 2:40-52.
Lindsay, David S., et al. (1993) "Neospora-Induced Protozoal Abortions in Cattle", The Compendium, 15(6) :882-889.
Conrad, Patricia A., et al. (1993) "Detection of serum antibody responses in cattle with natural or experimental Neospora infections", J. Vet Diagn Invest, 5:572-578.
Barr, B.C., et al. (1991) "Neospora-like Protozoal Infections Associated with Bovine Abortions", Vet Pathol, 28:110-116.
Conrad, P.A., et al. (1991) "In vitro isolation and characterization of a Neospora sp. from aborted bovine foetuses", Parasitology, 106:239-249.

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