Bovine immunoglobulin isolation process

Details Bovine immunoglobulin isolation process Bovine immunoglobulin isolation process

1974-12-02

1976-10-05

Rosen, Sam

Drug, bio-affecting and body treating compositions

Lymphokine

260112B, 424 85, A61K 3940, C07G 700

Patent

active

039845397

ABSTRACT:
A bovine immunoglobulin fraction for administration to calves to combat scours is prepared from bovine plasma or clear bovine serum by a process of salt fractionation of crude immunoglobulins and redissolving them in aqueous solution, heating the solution to 50.degree.-60.degree.C, cooling and removing coagulated proteins, precipitating out the immunoglobulins by salt fractionation, separating and redissolving the precipitate in aqueous solution, purifying the solution by subjection to a molecular sieve procedure, and sterile filtering.

REFERENCES:
patent: 2520076 (1950-08-01), Williams et al.
patent: 2543215 (1951-02-01), Williams et al.
patent: 3597409 (1971-08-01), Breuer

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