Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1987-12-31
1995-11-07
Schwartz, Richard A.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
530399, C12N 1518
Patent
active
054647746
ABSTRACT:
Substantially pure mammalian basic fibroblast growth factors are produced. The amino acid residue sequences of bovine and human bFGF are disclosed as well as a DNA chain encoding the polypeptide of the bovine species. By appropriately inserting a synthesized DNA chain into a cloning vector and using the cloning vector to transform cells, synthetic bovin bFGF can be obtained from transformed cell lines, both prokaryotic and eukaryotic.
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Baird Andrew J.
Bohlen Peter
Esch Frederick S.
Gospodarowicz Denis
Ling Nicholas C.
Gurian-Sherman Douglas
Schwartz Richard A.
The Salk Institute for Biological Studies
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