Botulinum toxin in treatment of clubfoot relapse

Details Botulinum toxin in treatment of clubfoot relapse Botulinum toxin in treatment of clubfoot relapse

2006-08-15

2010-10-26

Kam, Chih-Min (Department: 1656)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S236100, C424S009100, C514S002600, C514S012200, C530S350000, C435S252700

Reexamination Certificate

active

07820183

ABSTRACT:
Botulinum toxin, or other neuromuscular inhibitors, injected into the lower leg muscle of infants, less than a year old, with idiopathic clubfoot is shown to be an effective therapy in correcting this physical deformity. Following a protocol of manipulations, castings, and injections, clubfoot is effectively treated, and surgical treatment procedures can be avoided.

REFERENCES:
Alkjaer T, Pedersen EN, Simonsen EB. Evaluation of the walking pattern in clubfoot patients who received early intensive treatment. J Pediatr Orthop. 2000;20:642-647.
Applington JP, Riddle CD. Avascular necrosis of the body of the talus after combined medial and lateral release of congenital clubfoot. South Med J. 1976;69:1037-1038.
Asperheim MS, Moore N, Carroll NC, et al. Evaluation of residual clubfoot deformities using gait analysis. J Pediatr Orthop B. 1995;4:49-54.
Atar D, Lehman WB, Grant AD. Complications in clubfoot surgery. Orthop Rev. 1991;20:233-239.
Bakheit AM, Severa S, Cosgrove A, et al. Safety profile and efficacy of Botulinum toxin A (Dysport) in children with muscle spasticity. Dev Med Child Neurol. 2001;43:234-238.
Bang MS, Chung SG, Kim SB, et al. Change of dynamic gastrocnemius and soleus muscle length after block of spastic muscle in cerebral palsy. Am J Phys Med Rehabil. 2002;81:760-764.
Bensahel H, Guillaume A, Desgrippes Y. Results of physical therapy for idiopathic clubfoot: a longterm follow up.Journal of Pediatric Orthopaedics1990;10:189-192.
Brin MF, ed. Spasticity: etiology, evaluation, management, and the role of botulinum toxin A. Muscle Nerve. 1997;20(Supp 6):61-91.
Carroll NC. Surgical technique for talipes equinovarus. Oper Tech Orthop. 1993;3:115-120.
Chotel F, Parot R, Durand J, et al. Initial management of congenital varus clubfoot by Ponseti's method. Rev Chir Orthop Reparatrice Appar Mot. 2002;88:710-717.
Cooper DM, Dietz FR. Treatment of idiopathic clubfeet: a thirty-year follow-up note. J Bone Joint Surg [Am]. 1995;77:1477-1489.
Crawford AH, Marxen JL, Osterfeld DL. The Cincinnati incision; a comprehensive approach for surgical procedures of the foot and ankle in childhood. J Bone Joint Surg [Am]. 1982;64:1355-1358.
Delgado et al. A preliminary report of the use of botulinum toxin type A in infants with clubfoot: four case studies.Journal of Pediatric Orthopedics. 2000;20(4):533-8.
Delgado, M.R., et al., A preliminary report of the use of botulinum toxin type A in infants with clubfoot: fouir case studies, Journal of Pediatric Orthopedics, Jul.-Aug. 2000, vol. 20, No. 4, pp. 533-538.
Dimeglio A, Bensahel H, Souchet PH, Mazeau P, Bonnet F. Classification of clubfoot.Journal of Pediatric Orthopaedics(Br) 1995;4:129-136.
Eames NW, Baker R, Hill N, et al. The effect of botulinum A toxin on gastrocnemius length: magnitude and duration of effect. Dev Med Child Neurol. 1999;41:226-232.
Edgar TS. Clinical utility of botulinum toxin in the treatment of cerebral palsy: comprehensive review. J Child Neurol. 2001;16:37-46.
Flynn JM et al. An independent assessment of two clubfoot-classification systems.Journal of Pediatric Orthopedics. 18(3):323-7, 1998.
Goksan SB. Treatment of congenital clubfoot with the Ponseti method. Acta Orthop Traumatol Turc. 2002;36:281-287.
Hee HT, Lee EH, Lee GS. Gait and pedographic patterns of surgically treated clubfeet. J Foot Ankle Surg. 2001;40:287-294.
Herzenberg JE, Radler CR, Bor N. Ponseti versus traditional methods of casting for idiopathic clubfeet. J Pediatr Orthop. 2002;22:517-521.
Johnson L, ed. Essential Medical Physiology, 2nd ed. Philadelphia: Lippincott-Raven, 1998.
Juzans P, Comella JX, Molgo J, et al. Nerve terminal sprouting in botulinum A-treated mouse levator auris longus muscle. Neuromuscul Disord. 1996;6:177-185.
Karol LA, Concha MC, Johnston C.E.2nd. Gait analysis and muscle strength in children with surgically treated clubfeet.Journal of Pediatric Orthopaedics1997;6:790-795.
Klein AW. Complications and adverse reactions with the use of botulinum toxin. Semin Cutan Med Surg. 2001;20:109-120.
Koman LA, Mooney JF, Smith B, et al. Management of cerebral palsy with botulinum A toxin: preliminary investigation. J Pediatr Orthop. 1993;13:489-495.
Laaveg SJ, Ponseti IV. Long-term results of treatment of congenital clubfoot. J Bone Joint Surg [Am]. 1980;62:23-31.
McKay DW. New concept of and approach to clubfoot treatment: section II. Correction of the clubfoot. J Pediatr Orthop. 1983;3:10-21.
McNeer KW, Tucker MG, Spencer RF. Management of essential infantile esotropia with botulinum toxin A: review and recommendations. J Pediatr Ophthalmol Strabismus. 2000;37:63-67.
Miller JH, Bernstein SM. The roentogenographic appearance of the corrected clubfoot. Foot Ankle. 1986;6:177-183.
Mooney JF, Koman LA, Smith BP. Pharmacologic management of spasticity in cerebral palsy. J Pediatr Orthop. 2003;23:679-686.
Morrissy RT, Weinstein SL, eds. Lovell and Winter's Pediatric Orthopaedics, 2nd ed. Philadelphia: Lippincott-Raven, 1996.
Otis JC, Bohne WH. Gait analysis in surgically treated clubfoot. J Pediatr Orthop. 1986;6:162-164.
Piers, Mitchell D., et al., Selective botulinum toxin injection in the treatment of recurrent deformity following surgical correction of cloub foot—A preliminary report of 3 children, Acta Orthopaedica Scandinavica, vol. 75, No. 5, Oct. 2004, pp. 630-633.
Ponseti IV. Clubfoot management. J Pediatr Orthop. 2000;20:699-700.
Ponseti IV. Common errors in the treatment of congenital clubfoot. Int Orthop. 1997;21:137-141.
Ponseti IV. Congenital Clubfoot: Fundamentals of Treatment. New York: Oxford University Press, 1996.
Ponseti IV. Treatment of congenital clubfoot. J Bone Joint Surg [Am]. 1992;74:448-454.
Reiter, F, Danni, M., Lagalla, G., Ceravolo, G., Provinciali, L. 1998. Low dose botulinum toxin eith ankle taping for the treatment of spastic equinovarus foot after stroke. Arch Phys Med Rehabil 79:532-535.
Roye DP, Roye BD. Idiopathic congenital talipes equinovarus. J Am Acad Orthop Surg. 2002;10:239-248.
Schlafly B, Butler JE, Siff SJ. The appearance of the tarsal navicular after posteromedial release for clubfoot. Foot Ankle. 1985;5:222-237.
Scott AB. Botulinum A injection of eye muscles to correct strabismus. Trans Am Ophthalmol Soc. 1981;79:734-770.
Seringe R, Atia R. Idiopathic congenital clubfoot. Results of functional treatment.Revue de Chirurgie Orthopedique et Reparatrice de l'Appareil Moteur1990;76:490-501.
Souchet P, Bensahel H, Themar-Noel C, Pennecot G, Csukonyi Z. Functional treatment of clubfoot: A new series of 350 idiopathic clubfeet with long-term follow-up.Journal of Pediatric Orthopaedics(Br) 2004;13:189-196.
Turco VJ. Surgical correction of the resistant clubfoot: one-stage posteromedial release with internal fixation. A preliminary report. J Bone Joint Surg [Am]. 1971;53:477-497.
Widhe T, Berggren I. Gait analysis and dynamic foot pressure in the assessment of the treated clubfoot. Foot Ankle Int. 1994;15:186-190.
Alvarez, Christine M., et al.,Treatment of Idiopathic Clubfoot Utilizing Botulinum A Toxin, J. Pediatr Orthop, vol. 25, No. 2, Mar./Apr. 2005, pp. 229-234.
Bleck, E. Metatarsus adductus: Classification and relationship to outcomes of treatment. Journal of Pediatric Orthopedics 1983;3:2-9.
Carroll NC, McMurtry R, Leete SF. The pathoanatomy of congential clubfoot. Orthop Clin North Am. 1978;9:225-232.
Dobbs MB. A single surgeon's experience with the Ponseti method for the treatment of idiopathic clubfoot deformity. International Society of Orthopedic Surgery and Traumatology 3rd International Clubfoot Congress, San Diego, California, Aug. 2002.
Garceau, G, Palmer, R. Transfer of the anterior tibial tendon for recurrent clubfoot: A long-term follow-up. Journal of Bone and Joint Surgery 1967;49:207-31.
Garceau, G. Anterior tibial tendon transfer for recurrent clubfoot.Clinical ,Orthopedics and Related Research1 972;84:61 .5.
Karol LA, Concha MC, Johnston CE 2d. Gait analysis and muscle strength in children with surgically treated clubfeet. J Pediatric Orthopetic. 1997;6:790-795.
Lehman WB, Scher DM, Feldman DS, et al. Method of evaluating the effectiveness of the Iowa (Ponseti) club

Affiliated with

Also associated with

Rating

Botulinum toxin in treatment of clubfoot relapse does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Botulinum toxin in treatment of clubfoot relapse, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Botulinum toxin in treatment of clubfoot relapse will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4215007