Botcinol: a natural product herbicide

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Fungus

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504291, 504271, 4352541, C12N 114

Patent

active

056793413

ABSTRACT:
A novel organic compound, designated botcinol, has been isolated which possesses significant phytotoxic activity and which may be used as a biodegradable contact herbicide. The compound is a hydroxylated nonalactone that is esterified with 4-hydroxy-2-decenoic acid, and has the following structure: ##STR1## Botcinol is produced by culture of a novel strain of the fungus Botrytis cinerea, designated UK 185, and may be subsequently recovered from the culture medium and purified.

REFERENCES:
Abstract, Proceedings, Nineteenth Annual Meeting, Plant Growth Regulator Society of America, San Francisco, CA, Jul. 17-20, 1992, "Isolation of a New Biologically-Active Metabolite from Botrytis cinerea", H. G. Cutler, et al., published May 1993.
Cutler, Horace G., et al. "Botcinolide: A Biologically Active Natural Product from Botrytis cinerea", Biosci. Biotech. Biochem., 11, vol. 57, pp. 1980-1982, Nov. 1993.
Williamson, B. and Duncan, G.H., "Use of cryo-techniques with scanning electron microscopy to study infection of mature red raspberry fruits by Botrytis cinerea", New Phytol, 1989, 111, pp. 81-89.
Goodman, B.A., et al., "Non-invasive observation of the development of fungal infection in fruit", Protoplasms, 1992, 166, pp. 107-109.
El-Dei, Ala, et al., "Serological Studies on Some Isolates of Botrytis cinerea and other Botrytis Species", Phytopathologica Academiae Scientiarum Hungaricae, vol. 20(1-2), 1985, pp. 163-173.

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