Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of...
Patent
1993-05-27
1995-07-18
Sidberry, Hazel F.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
424 931, 4242341, C12N 100, C12N 120, A61K 3902
Patent
active
054340772
ABSTRACT:
The present invention provides a vaccine against Lyme disease, wherein it contains one or more monoclonal antibodies which are specific for the 31 kD antigen (OspA) or the 34 kD antigen (OspB) of Borrelia burgdorferi.
The present invention also provides a process for obtaining this vaccine, as well as new monoclonal antibodies and antigens.
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Fikrig et al., "Protection of Mice Against the Lyme Disease Agent by Immunizing with Recombinant OspA", Science, Oct. 1990, p., 553.
Simon et al., "A mouse model for Borrelia burgdorfer infection: approach to a vaccine against Lyme disease", Immunology Today, vol. 12, No. 1 1991, p. 11.
Eichmann Klaus
Kramer Michael
Reinhard Wallich
Schaible Ulrich E.
Simon Markus M.
Deutsches Krebsforschungszentrum Stiftung des Offentlichen Recht
Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.v.
Sidberry Hazel F.
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