Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1995-01-20
1997-11-18
Sidberry, Hazel F.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
4242621, 4241841, 4241851, 530350, 435 693, A61K 3900, A61K 3902, C07K 1400, C07K 1420
Patent
active
056885121
ABSTRACT:
Disclosed and claimed are substantially pure OspA, vaccines including substantially pure OspA and an immunologically acceptable carrier or vehicle, methods for producing such vaccines, and methods for inducing a protective immunological response against Borrelia burgdorferi employing such vaccines. The methods for producing the vaccines can include admixing the OspA and the carrier or vehicle. The methods for producing the vaccines also can include recovering the OspA from a host organism transformed with a vector containing DNA encoding the OspA and admixing the OspA with an immunologically acceptable carrier or vehicle. Such methods can further include adding an adjuvant. The vaccine can contain OspA from two or more strains of Borrelia burgdorferi.
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Barbour Alan G.
Bergstrom Sven
Kowalski Thomas J.
Sidberry Hazel F.
Symbicom Aktiebolag
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