Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1997-04-11
1998-11-03
Marschel, Ardin H.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 6, 536 243, 536 271, 536 2711, 536 2713, C07H 1900, C07H 2104, C12Q 168
Patent
active
058310452
ABSTRACT:
Modified nucleotides and polynucleotides which are useful in hybridization assays for the detection of target genes are provided. The modified polynucleotides contain at least one boronic acid moiety which is attached to a nucleotide base in a position which does not interfere with the hydrogen bonding capabilities of that base during duplex formation. The modified polynucleotides are typically formed from naturally occurring nucleotides and one or more modified nucleotides.
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Kaiser Robert J.
Stolowitz Mark L.
Marschel Ardin H.
Porlinx, Incorporated
Riley Jezia
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