Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2011-03-29
2011-03-29
Ward, Paul V. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C540S145000, C424S009100
Reexamination Certificate
active
07915248
ABSTRACT:
The present invention relates to metal-phthalocyanines bearing at least a group containing boron isotopes11B or10B, covalently bound to the axial positions of metal-phthalocyanine nucleus; moreover it refers to the process for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies in PDT and/or BNCT.
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Kahl et al, “Synthesis and Characterization of a Boranted Metallophthalocyanine for Boron Neutron Capture Therapy,” Inorganic Chemistry, 1996, 35, 3878-3880.
Fabris et al., “Photosensitizing properties of a boronated phthalocyanine: studies at the molecular and cellular level,” Journal of Photochemistry and Photobiology B: Biology 64 (2001) 1-7.
Chiti Giacomo
Dei Donata
Jori Giulio
Municchi Moira
Nistri Daniele
Abelman ,Frayne & Schwab
L. Molteni & C. Dei Fratelli Alitti Societa'Di Esercizio S.
Ward Paul V.
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