Boron heterocycle steroid mimics and associated pharmaceutical c

Details Boron heterocycle steroid mimics and associated pharmaceutical c Boron heterocycle steroid mimics and associated pharmaceutical c

1999-01-25

2000-07-04

McKane, Joseph

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Boron containing doai

558269, 558289, 564 11, A01N 5558, C07C 6996, C07F 504, C07F 502

Patent

active

060839368

ABSTRACT:
Boron heterocycle steroid mimics are provided that are useful as pharmaceutical agents, particularly in the treatment of estrogen-dependent disorders such as estrogen-dependent cancers. The compounds are also useful in diagnostic techniques such as magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS), in boron neutron capture therapy, and in fluorescence emission-based modalities. Pharmaceutical formulations and methods of using the novel compounds are provided as well.

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