Borage seed oil as an anti-irritant in compositions containing h

Details Borage seed oil as an anti-irritant in compositions containing h Borage seed oil as an anti-irritant in compositions containing h

1996-08-30

1997-11-25

Schofer, Joseph L.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Cosmetic, antiperspirant, dentifrice

424 59, 424 69, 514772, 514844, A61K 740

Patent

active

056909470

ABSTRACT:
Compositions containing hydroxy acids and/or retinoids and further containing borage seed oil as an anti-irritant. Borage seed oil was found to be uniquely effective (when compared to gamma-linolenic acid, or other anti-irritants containing gamma-linolenic acid or other known anti-irritants) in reducing the irritation caused by hydroxy acids and/or retinoids.

REFERENCES:
patent: 5039513 (1991-08-01), Chatterjee
patent: 5082661 (1992-01-01), Melnik
patent: 5252604 (1993-10-01), Nagy et al.
patent: 5310556 (1994-05-01), Ziegler
patent: 5445822 (1995-08-01), Bracco
patent: 5476661 (1995-12-01), Pillai et al.
patent: 5516793 (1996-05-01), Duffy
patent: 5587149 (1996-12-01), Punto
Derwent Abstract of FR 2704390 dated Nov. 4, 1994.
Derwent Abstract of FR 2604624 dated Apr. 8, 1988.
Derwent Abstract of GB 2271928 dated May 4, 1994.
Medline Abstract of Tollesson et al., "Transepidermal Water Loss and Water Content in the Stratum Corneum in Infantile Sebhorroeic Dermatitis", Acta Derm Venereol (Sweden), Feb. 1993, 73 (1), pp. 18-20.
Medline Abstract of Bahmer et al., "Treatment of Atopic Dermatitis with Borage Seed Oil (Glandol)--A Time Series Analytic Study", Kinderarztl Prax (Germany), Oct. 1992, 60 (7), pp. 199-202.
Ingredient Label 1: A composition marketed more than 1 year prior to filing of the present application.

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