Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1994-07-01
1997-06-24
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514 92, 514152, 548112, 548118, 548119, 552203, C07F 96539, C07D28512, A61K 3165, A61K 31675
Patent
active
056417624
ABSTRACT:
The present invention relates to novel compounds useful for the treatment and prophylaxis of degenerative bone disorders and to the preparation thereof. These compounds are particularly characterized by two active moieties, the first of which possesses "bone-seeking" affinity and the second which is an inhibition of the enzyme carbonic anhydrase and/or an inhibitor of bone resorption. The novel compounds of this invention can be administered as pharmaceutically acceptable compositions and in convenient dosage unit form in a method for the treatment and prophylaxis of degenerative bone disorders.
REFERENCES:
patent: 4687767 (1987-08-01), Bosies
patent: 4876248 (1989-10-01), Breliere
Pierce, Jr. William M.
Waite Leonard C.
Gerstl Robert
Research Corporation Technologies Inc.
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