Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1996-12-11
2000-09-12
Kemmerer, Elizabeth
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 13, 514 14, 514 15, 530300, 530350, A61K 3813, C07K 1400
Patent
active
06117839&
ABSTRACT:
Polypeptides which stimulate bone growth: Gly Ile Gly Lys Arg Thr Asn Glu His Thr Ala Asp Cys Lys Ile Lys Pro Asn Thr Leu His Lys Lys Ala Ala Glu Thr Leu Met Val Leu Asp Gln Asn Gln Pro (SEQ ID NO:1) and subsequences, particularly Arg Thr Asn Glu His Thr Ala Asp Cys Lys (SEQ ID NO:9) and associated nucleotide sequences, methods of preparation and use, antibodies and kits.
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Noda et al. In vivo stimulation of bone formation by transforming growth factor-beta. Endocrinology, (Jun. 1989) 124(6) 2991-4.
A. Walz et al., "Generation of the Neutrophil-Activating Peptide NAP-2 from Platelet Basic Protein or Connective Issue-3 Activating Peptide III Through Monocyte Proteases", Journal of Med., vol. 171, Feb. 1990, pp. 449-454.
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C.W. Castor et al., "Structural and Biological Chacteristics of Connective Tissue Activating Peptide (CTAP-III), a Major Human Platelet-3 derived Growth Factor", Proc. Natl. Acad. Sci. USA, vol. 80, Fed. 1983, pp. 765-769.
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Gensci Regeneration Sciences Inc.
Kemmerer Elizabeth
Romeo David S.
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