Bone seeking technetium 99m complex

Details Bone seeking technetium 99m complex Bone seeking technetium 99m complex

1976-02-13

1978-04-04

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

2523011R, 423249, 250303, A61K 4300, A61K 2900

Patent

active

040828409

ABSTRACT:
A technetium-99m-stannous-phosphate complex in which the phosphate moiety includes pyrophosphate and in which no more than 5 to 15% or 20% by weight of such phosphate moiety is a linear polyphosphate of molecular weight greater than pyrophosphate, a method of making the same, a method of using the same by in vivo intravenous administration to a mammal of the sterile, nonpyrogenic complex followed by radioassay scanning or imaging the skeletal structure, and a kit made up of a stannous-phosphate complex in which the phosphate moiety is pyrophosphate and in which no more than 5 to 15% or 20% by weight of such phosphate moiety is a linear polyphosphate of molecular weight greater than pyrophosphate.

REFERENCES:
subramanian et al., Radiology, vol. 99, No. 1, Apr. 1971, pp. 192-196.

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