Bone-seeking complexes of Technetium-99m

Details Bone-seeking complexes of Technetium-99m Bone-seeking complexes of Technetium-99m

1984-04-16

1987-02-10

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 9, 534 14, 2605024P, A61K 4300, A61K 4900, A61K 4902

Patent

active

046422293

ABSTRACT:
A bone-seeking, Technetium-99m-ethylene glycol-1,2-bisphosphonate complex has been found to be useful as a bone-scanning agent. The complex, which is prepared by adding Technetium-99m, as an aqueous solution of pertechnetate, to a composition comprising a mixture of ethylene glycol-1,2-bisphosphonic acid or a non-toxic salt thereof with a reducing agent for pertechnetate, is taken up rapidly in bone to give scans of high definition and compares favorably in this and other respects to other bone-scanning agents.

REFERENCES:
patent: 3983227 (1976-09-01), Tofe et al.
patent: 4088747 (1978-05-01), Hunt et al.
patent: 4187284 (1980-02-01), Rollestone et al.
patent: 4387087 (1983-06-01), Deutsch et al.
patent: 4515766 (1985-05-01), Castronovo et al.

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