Bone replacement material comprising crystalline and X-ray...

Details Bone replacement material comprising crystalline and X-ray... Bone replacement material comprising crystalline and X-ray...

2003-10-20

2009-06-16

Azpuru, Carlos A (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

Reexamination Certificate

active

07547448

ABSTRACT:
The present invention relates to an X-ray amorphous-crystalline material with high solubility which can be used as a bioactive bone replacement material and as a substrate material in biotechnology. The new material comprising crystalline and X-ray amorphous phases is characterized in that according to31P-NMR measurements, it contains Q0-groups of orthophosphate and Q1-groups of diphosphate, the ortho-phosphates or Q0-groups making up 70 to 99.9% by weight relative to the total phosphorus content of the finished material and the diphosphates or Q1-groups making up 0.1 to 30% by weight relative to the total phosphorus content of the finished material, and that according to X-ray diffractometric measurements and relative to the total weight of the finished material, 30 to 99.9% by weight of a main crystal phase consisting of Ca2K1−xNa1+x(PO4)2, where x=0.1 to 0.9, is contained in the bone replacement material and 0.1 to 20% by weight of a substance selected from the group consisting of Na2CaP2O7, K2CaP2O7, Ca2P2O7and mixtures thereof is contained as a secondary crystal phase, the X-ray amorphous phases contained besides the main crystal phase jointly making up 0.1 to 70% by weight relative to the total weight of the finished material.

REFERENCES:
patent: 3922155 (1975-11-01), Hans-Herbert et al.
patent: 6117456 (2000-09-01), Lee et al.
patent: 7223420 (2007-05-01), Berger et al.
patent: 0 237 043 (1992-06-01), None
patent: 91/07357 (1991-05-01), None
patent: W0 91/07357 (1991-05-01), None
“Morphological Evaluation of Osteoblasts Cultured On Different Calcium Phosphate Ceramics”, Knabe C. et al, Biomaterials, Elsevier Science Publishers BV., Barking, GB (1997) No. 20, pp. 1339-1347.

Affiliated with

Also associated with

Rating

Bone replacement material comprising crystalline and X-ray... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Bone replacement material comprising crystalline and X-ray..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bone replacement material comprising crystalline and X-ray... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4104776