Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1996-10-25
1999-02-09
Hutzell, Paula K.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 234, 435 691, 435 697, 435325, 4352551, 4352523, 43525233, C07H 2102, C07H 2104
Patent
active
058696385
ABSTRACT:
A bone-related protein named OSF-4 which is obtained from bone tissue of a mammal including mouse or human, and a process for its production. This protein is a novel naturally occurring mammal protein of the cadherin family.
OSF-4 acts as an adhesion molecule or a growth factor which takes part in the process of osteogenesis at the site of bone induction. OSF-4 can be used as an agent for treating bone metabolic diseases, and its high organ specificity for bones enables its use as a diagnostic reagent for bone metabolic diseases.
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"Cadherin Cell Adhesion Receptors as a Morphogenetic Regulator", Masatoshi Takeichi, Science, 251:1451-1455 (1991).
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Ranscht, b et al., Medline Abstract, Accession No. 92000685 for Neuron 7(3): 391-402, 1991.
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Amann Egon
Kawai Shinji
Okazaki Makoto
Takeshita Sunao
Tsujimura Atsushi
Bakalayar Heather A.
Hoechst Japan Limited
Hutzell Paula K.
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