Bone reinforcing agent and foods and drinks product containing t

Details Bone reinforcing agent and foods and drinks product containing t Bone reinforcing agent and foods and drinks product containing t

1995-09-22

1999-08-03

Wong, Leslie

Food or edible material: processes, compositions, and products

Fermentation processes

Of milk or milk product

426 41, 426656, 426657, 426800, A23C 912

Patent

active

059322594

ABSTRACT:
A bone reinforcing agent comprising a basic protein fraction or a basic peptide fraction derived from milk as an effective component is described. The basic protein fraction is obtained by passing milk or a raw material derived from milk over a cation exchange resin and eluting the adhered fraction. The basic peptide fraction is obtained by hydrolyzing the basic protein fraction with a protease. The basic protein fraction and basic peptide fraction of the present invention promote the growth of osteoclasts and suppress the resorption of osteoclasts, and thereby strengthening bone when administered orally. The invention is useful for treating or preventing bone diseases such as osteoporosis.

REFERENCES:
patent: 3970520 (1976-07-01), Feldman et al.
patent: 4107334 (1978-08-01), Jolly
patent: 5149647 (1992-09-01), Burling
patent: 5516675 (1996-05-01), Uchida et al.
K. Kussendrager, "Lactoferrin and Lactoperoxydase, Bio-Active Milk Proteins" IFI NR.6, pp. 17-21 (1993).
S. Rudloff et al., "Calcium Retention from Milk-Based Infant Formulas, Whey-Hydrolysate Formula, and Human Milk in Weanling Rhesus Monkeys" AJDC 144:360-363 (1990).

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