Bone morphogenetic protein (BMP)-17 and BMP-18 compositions

Details Bone morphogenetic protein (BMP)-17 and BMP-18 compositions Bone morphogenetic protein (BMP)-17 and BMP-18 compositions

1997-12-10

2000-02-22

Kemmerer, Elizabeth C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4352523, 435325, 536 235, 536 2351, C12N 121, C12N 510, C12N 1512, C12N 1563

Patent

active

060279176

ABSTRACT:
Purified BMP-17 and BMP-18 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-17 and BMP-18 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, epithelium, brain, spleen, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.

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