Bone morphogenetic protein 3 and osteogenic devices and...

Details Bone morphogenetic protein 3 and osteogenic devices and... Bone morphogenetic protein 3 and osteogenic devices and...

2006-05-26

2010-12-14

Kemmerer, Elizabeth C. (Department: 1646)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S351000, C536S023100, C536S023500, C435S320100, C435S252300, C435S254110, C435S325000

Reexamination Certificate

active

07851435

ABSTRACT:
The present invention relates to reindeer bone formation inducing protein called bone morphogenetic protein 3c (BMP-3c), nucleotide molecules encoding the protein and host cells expressing the protein. The present invention relates also to the use of said BMP-3c for treating disorders related to bone and cartilage formation. Osteogenic devices and pharmaceutical compositions containing the protein are also disclosed.

REFERENCES:
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patent: 94/01557 (1994-01-01), None
patent: WO 2004/061125 (2004-07-01), None
Uniprot database entry Q08DX6, bovine bone morphogenic protein-3b, May 2007.
Wells, 1990, Biochemistry 29:8509-8517.
Ngo et al., 1994, The Protein Folding Problem and Tertiary Structure Prediction, Merz et al., eds., Birkhauser, Boston, pp. 492-495.
European search report dated Feb. 2, 2009 in corresponding EP 06725969.
Database EMBL [Online], Mar. 11, 2005, “1254007 MARC 7BOV Bos taurus cDNA 5;, mRNA sequence”, XP002513027.
Kapanen A et al., “Bone morphogenetic protein 3b expressing reindeer antler”, Journal of Biomedical Materials Research Jan. 2002, vol. 59, No. 1, Jan. 2002, pp. 78-83, XP002513026.
Takao M et al., “Identification of rat bone morphogenetic protein -3b (BMP-3b), a new member of BMP-3”, Biochemical and Biophysical Research Communications, Academic Press Inc., vol. 219, No. 2, Jan. 1, 1996, pp. 656-662, XP002351080.
European Search Report in Corresponding Application No. 06725969.7 Dated Apr. 20, 2010.

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