Bone induction method

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Bone

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623 66, 623 11, A61F 228, A61F 202

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053063031

ABSTRACT:
A method of inducing bone growth in a living animal consists of implanting in the soft tissue or bone of the animal a bone morphogenetic protein-free, ceramic consisting of a calcium phosphate which is at least partially resorbable, and leaving the ceramic in place until new bone growth is induced.

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Lynch et al., "Osteoinductivity by Subcutaneous Implantation of a Collagen/Ceramic Composite," 3rd International Symposium on Ceramics in Medicine, Abstracts (Nov. 18-20, 1990).
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Ohgushi et al. Journal of Orthopaedic Research, 7:568-578 (1989).
"Osteoinductivity by Subcutaneous Implantation of a Fibrillar Collagen and Calcium Phosphate Ceramic Composite", Lynch et al., pp. 295-304, Bioceramics, vol. 3, Apr. 1992.
"Biologic Principles of Bone Induction," A. H. Reddi et al., pp. 207-212, Bone Grafting, Orthopedic Clinics of North America, vol. 18, No. 2, Apr. 1987.
"Bona Fide Osteoinductive Factors," A. H. Reddi et al., The Journal of NIH Research, vol. 2 pp. 67-70, May 1990.
Pp. 692-703, The Journal of Bone and Joint Surgery, Incorporated, vol. 73A, No. 5, Jun. 1991.
"Composite Grafts of Human Bone Marrow Cells and Porous Ceramics," Ohgushi et al., pp. 279-285, Bioceramics, vol. 3, Nov. 20, 1992.

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