Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Bone
Reexamination Certificate
2008-02-11
2009-06-09
Monshipouri, Maryam (Department: 1656)
Prosthesis (i.e., artificial body members), parts thereof, or ai
Implantable prosthesis
Bone
Reexamination Certificate
active
07544212
ABSTRACT:
A bone implant composite comprising a collagen matrix and a calcium-based mineral, the calcium-based mineral having a particle size of 25-2000 μm and being interspersed in the collagen matrix; wherein the bone implant composite contains 3-60% by weight the collagen matrix and 40-97% by weight the calcium-based mineral, and has a pore size of 50-500 μm, a density range of 0.02-0.8 g/cm3, a tensile strength range of 0.4-100 kg/cm2, and a compression modulus range of 0.2-10 kg/cm2. Also disclosed are methods of preparing the above-described composite.
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Chen et al., “A Collagen-Anorganic Bone Composite for Bone Repair: Part I. In Vitro Characterization Studies,” Transactions of the 31stAnnual Meeting of the Society of Biomaterials, vol. XXIX (Apr. 2006).
Speer et al., “A Collagen-Anorganic Bone Composite for Bone Repair: Part II: In Vivo Study in a Rabbitt Radius Defect Model,” Transactions of the 31stAnnual Meeting of the Society of Biomaterials, vol. XXIX (Apr. 2006).
Chen Hui-chen
Li Shu-tung
Yuen Debbie
Collagen Matrix, Inc.
Monshipouri Maryam
Occhiuti Rohlicek & Tsao LLP
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