Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Reexamination Certificate
2011-03-01
2011-03-01
Kemmerer, Elizabeth C. (Department: 1646)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
C514S007600, C514S008800, C514S008900, C514S009100, C514S016700, C514S019100, C514S020600, C514S001100
Reexamination Certificate
active
07897163
ABSTRACT:
The present invention relates to a bone graft material and a scaffold for tissue engineering applications, which have an osteogenesis-promoting peptide immobilized on the surface. More particularly, the invention relates to a bone graft material and a scaffold for tissue engineering applications, which have a cell adhesion-inducing peptide and/or tissue growth factor-derived peptide immobilized on the surface. By the osteogenesis-promoting peptide immobilized on the surface, the inventive bone graft material and scaffold for tissue engineering applications can promote the transition, proliferation and differentiation of cells associated with regeneration, and eventually maximize the regeneration of tissue. Moreover, the peptide immobilized on the surface has low molecular weight, indicating a reduced risk of immune responses upon its application in the body, and can be present in a stable form within the body, thus showing lasting effects. Accordingly, the peptide makes it expedient to perform surgical operations for the regeneration of periodontal tissue, alveolar bone and other bone tissues, and will show high therapeutic effect.
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Chung Chong-Pyoung
Lee Seung Jin
Park Yoon Jeong
Rhee Sang Hoon
Hultquist Steven J.
Intellectual Property / Technology Law
Kemmerer Elizabeth C.
Reynolds Kelly K.
Seoul National University Industry Foundation
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