Bone cement compositions containing gentamycin

Details Bone cement compositions containing gentamycin Bone cement compositions containing gentamycin

1976-02-09

1977-11-22

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

424 14, 424 81, 536 17, A61K 3178

Patent

active

040596842

ABSTRACT:
A bone cement composition includes, as the principal component, powdered copolymers of methyl methacrylate and methyl acrylate, or monomeric methyl methacrylate, and, in addition, gentamicin hydrochloride and/or gentamicin hydrobromide, or a mixture of gentamicin sulfate with sodium chloride, potassium chloride, sodium bromide and/or potassium bromide. The bone cement composition is used, for example, for cementing implants in place, for the anchoring of endoprostheses of the joints, in the treatment of skull defects, and for carrying out spinal fusions. The composition provides for antibiotic release in higher concentrations to prevent infections.

REFERENCES:
patent: 3915955 (1975-10-01), Cooper et al.

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