Bone cement composition

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Processes of preparing a desired or intentional composition...

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523115, 523117, 523206, 523207, 523211, 427203, 427214, 427222, A61K 608, A61F 200, B05D 136, B05D 700

Patent

active

055126103

ABSTRACT:
A bone cement composition has adjustable rheological properties, high strength, and produces a uniform radiological image. The cement is characterized by controlled retention and release of additives incorporated in beads included in the dry component of the cement. The cement comprises beads containing a polymerization initiator in controllable concentrations from 0% to 5% or more by weight. These same beads or others may also contain an opacifier. The polymerization initiator and the opacifier may be selectively distributed throughout the beads or at specific radial locations in the beads. They may also be selectively placed in beads of a particular advantageous size range. Furthermore, in other embodiments of the invention, other advantageous additives can be incorporated in the beads such as dyes, antibiotics, bone growth factors, and other pharmacological or therapeutic agents.

REFERENCES:
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patent: 4045403 (1977-08-01), Lever et al.
patent: 4404327 (1983-09-01), Crugnola et al.
patent: 4456711 (1984-06-01), Pietsch et al.
patent: 4500658 (1985-02-01), Fox
patent: 4535485 (1985-08-01), Ashman et al.
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patent: 4791150 (1988-12-01), Braden et al.
patent: 5051482 (1991-09-01), Tepic
patent: 5061520 (1991-10-01), Hermelin
Literature-Howmedica-Surgical Simplex P Bone Cement-No date available.
Literature-Zimmer-Zimmer Bone Cement-Feb. 1978.
Literature-Richards-Palacos R-No date available.
Literature-Zimmer-Chemistry of Cement Settings-No date available.

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