Bone-associated transcription control factor-like protein

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Hormones – e.g. – prolactin – thymosin – growth factors – etc.

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530350, 930 10, C07K 1451

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active

055787088

ABSTRACT:
Bone-associated proteins derived from bone of mammals, including mice and human beings, named OSF-6. The protein is the novel natural type mammal protein, which can play an important role in bone formation, and belongs to a group of transcription control factors.
OSF-6 can be used as a therapeutic agent for bone metabolic diseases, and also as a diagnostic agent for bone metabolic diseases, since it may demonstrate a high organ specificity to bone.

REFERENCES:
patent: 5460951 (1995-10-01), Kawai et al.
Gieffers et al. (1993) Euro. J. of Cell Biol. 62(2):352-361.
Katoh et al. (1992) DNA and Cell Biol. 11(10):735-743.
Kawai et al. (1994) J. Biochem. 115:641-643.
Takamatsu et al. (1992) Biochem. Biophys. Res. Comm. 185(1):224-230.
Takeshita et al. (1993) Biochem. J. 294:271-278.
Tezuka et al. (1990) Biochem. Biophys. Res. Comm. 173(1):246-251.

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