Boholmycin antibiotic

Details Boholmycin antibiotic Boholmycin antibiotic

1986-01-08

1988-12-20

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 168, 536 172, 536 179, 435 82, 435 83, A61K 3171, C07H 1520

Patent

active

047925450

ABSTRACT:
Boholmycin antibiotic is prepared by fermentation of Streptomyces hygroscopicus H617-25 (ATCC No. 53240) in a nutrient medium preferably comprising glycerol, bacto-liver, cornsteep liquor, ammonium sulfate, sodium chloride and calcium carbonate. The antibiotic and pharmaceutically acceptable salts and hydrates thereof and compositions containing these are effective against Gram-positive, Gram-negative and acid-fast bacteria and against bacterial strains which are resistant to previously known aminoglycoside antibiotics and are useful to treat bacterial infections in mammals.

REFERENCES:
patent: 4468386 (1984-08-01), Hanada et al.
patent: 4656160 (1987-04-01), Takaya et al.
J. Antibiotics 29(11), Sorbistin, A New Aminoglycoside Antibiotic Complex of Bacterial Origin, Hiroshi Tsukiura et al., pp. 1137-1146.

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