BMP-1 procollagen c-proteinase for diagnosis and treatment...

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S139100

Reexamination Certificate

active

07850964

ABSTRACT:
Uses of BMP-1 isoforms for diagnosing and treating defects and disorders of bone and soft tissues are described. Also described is a newly isolated variant of the BMP-1 isoform BMP-1-3.

REFERENCES:
patent: 4968590 (1990-11-01), Kuberasampath et al.
patent: 5011691 (1991-04-01), Oppermann et al.
patent: 5496552 (1996-03-01), Kuberasampath et al.
patent: 5674844 (1997-10-01), Kuberasampath et al.
patent: 6333312 (2001-12-01), Kuberasampath et al.
patent: 2003/0215836 (2003-11-01), Young et al.
patent: 2003/0224501 (2003-12-01), Young et al.
patent: 2005/0147602 (2005-07-01), Lindner
Applicant's Response to the Written Opinion as filed for international application No. PCT/US2007/016605 on Dec. 19, 2008.
International Search Report for international application No. PCT/US2007/016605(Sep. 19, 2008).
Written Opinion of the International Searching Authority for international application No. PCT/US2007/016605 (Sep. 19, 2008).
Bonnarens et al., Production of a Standard Closed Fracture in Laboratory Animal Bone,J. Orthop. Res.,2: 97-101 (1984).
Borovecki et al., “The role of bone morphogenetic proteins in kidney development and repair” InBone Morphogenetic Proteins From Laboratory to Clinical Practice, (Vukicevic and Sampth, eds.) (Birkhäuser Verlag, Basel, 2002), pp. 263-288.
Ge et al., GDF11 Forms a Bone Morphogenetic Protein 1-Activated Latent Complex That Can Modulate Nerve Growth Factor-Induced Differentiation of PC12 Cells,Mol. Cell. Biol.,25(14): 5846-5858 (2005).
Griffith et al., Three-dimensional structure of recombinant human osteogenic protein 1: Structural paradigm for the transforming growth factor β superfamily,Proc. Natl. Acad. Sci. USA, 93: 878-883 (1996).
Greenspan, Biosynthetic Processing of Collagen Molecules,Top. Curr. Chem.,247: 149-183 (2005).
Greenspan et al., Developmental Roles of the BMP1/TLD Metalloproteinases,Birth Defect Res.(Part C), 78: 47-68 (2006).
Grgurevic et al., Urine release of systemically administered bone morphogenetic protein hybrid molecule,J. Nephrol.,20: 311-319 (2007).
Hildebrand et al., Quantification of Bone Microarchitecture with the Structure Model Index,Comp. Meth. Biochem. Eng.,1: 15-23 (1997).
Hillman et al., An unappreciated role of RNA surveillance,Genome Biol.,5(R8): 1-16 (2004).
Hoffmann et al., Perspectives in the biological function, the technical and therapeutic application of bone morphogenetic proteins,Appl. Microbiol. Biotechnol.,57: 294-308 (2001).
Holliger et al., “Diabodies”: Small bivalent and bispecific antibody fragmentsProc. Natl. Acad. Sci. USA, 90: 6444-6448 (1993).
Iozzo, Basement Membrane Proteoglycans: From Cellar to Ceiling,Nat. Rev. Mol. Cell. Biol.,6: 646-656 (2005).
Janitz et al., Three alternatively spliced variants of the gene coding for the human bone morphogenetic protein-1,J. Mol. Med.,76: 141-146 (1998).
Kessler et al., Bone Morphogenetic Protein-1: The Type I Procollagen C-Proteinase,Science, 271: 360-362 (1996).
Leighton et al., Paired Basic/Furin-like Proprotein Convertase Cleavage of Pro-BMP-1 in thetrans-Golgi Network,J. Biol. Chem.,278(20): 18478-18484 (2003).
Li et al., The C-proteinase that processes procollagens to fibrillar collagens is identical to the protein previously identified as bone morphogenic protein-1,Proc. Natl. Acad. Sci.,93: 5127- 5130 (1996).
Marques et al., Production of a DDP Activity Gradient in the Early Drosophila Embryo through the Opposing Actions of the SOG and TLD Proteins,Cell, 91: 417-426 (1997).
Martinovic et al., Requirement of a bone morphogenetic protein for the maintenance and stimulation of osteoblast differentiation,Arch. Cytol. Histol.,1: 23-36 (2006).
Oslen et al., Improved peptide identification in proteomics by two consecutive stages of mass spectrometric fragmentation,Proc. Natl. Acad. Sci. USA, 101(37): 13417-13422 (2004).
Paralkar et al., An EP2 receptor-selective prostaglandin E2agonist induces bone healing,Proc. Natl. Acad. Sci. USA, 100(11): 6736-6740 (2003).
Reddi, BMP-1: Resurrection As Procollagen C-Proteinase,Science, 271: 463 (1996).
Reddi, J., Bone Morphogenetic Proteins: From Basic Science to Clinical Applications,J. Bone Joint Surg.,83-A (Supp.1): S-1—S-6 (2001).
Sampath et al., Dissociative extraction and reconstitution of extracellular matrix components involved in local bone differentiation,Proc. Natl. Acad. Sci. USA, 78(12): 7599-7603 (1981).
Sampath et al., Homology of bone-inductive proteins from human, monkey, bovine, and rat extracellular matrix,Proc. Natl. Acad. Sci. USA, 80: 6591-6595 (1983).
Sampath et al., Isolation of osteogenin, an extracellular matrix-associated, bone-inductive protein, by heparin affinity chromatography,Proc. Natl. Acad. Sci. USA, 84: 7109-7113 (1987).
Sieron et al., Structure and Function of Procollagen C-Proteinase (mTolloid) Domains Determined by Protease Digestion, Circular Dichroism, Binding to Procollagen Type I, and Computer Modeling,Biochem.,39: 3231-3239 (2000).
Simic et al., Systemically Administered Bone Morphogenetic Protein-6 Restores Bone in Aged Ovariectomized Rats by Increasing Bone Formation and Suppressing Bone Resorption,J. Biol. Chem.,281(35): 25509-25521 (2006).
Takahara et al., Bone Morphogenetic Protein-1 and a Mammalian Tolloid Homologue (mTld) Are Encoded by Alternatively Spliced Transcripts Which Are Differentially Expressed in Some Tissues,J. Biol. Chem.,269(51): 32572-32578 (1994).
Urist et al.,Human Bone Morphogenetic Protein (hBMP)1(41630),Proc. Soc. Exp. Biol. Med.,173: 194-199 (1983).
Vukicevic et al., Osteogenic Protein-1 (Bone Morphogenetic Protein-7) Reduces Severity of Injury After Ischemic Acute Renal Failure in Rat,J. Clin. Invest.,102(1): 202-214 (1998).
Vukicevic et al., Stimulation of the expression of osteogenic and chondrogenic phenotypes in vitro by osteogenin,Proc. Natl. Acad. Sci. USA, 86: 8793-8797 (1989).
Wolfman et al., Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases,Proc. Natl. Acad. Sci. USA, 100(26): 15842-15846 (2003).
Wozney et al., Novel Regulators of Bone Formation: Molecular Clones and Activities,Science, 242: 1528-1534 (1988).
International Preliminary Report on Patentability (Chapter II), issued Jan. 20, 2010, in international application No. PCT/US2007/016605 (including Annex).
Extended European Search Report dated Mar. 10, 2010, issued in corresponding European application No. 07836198.7.
Chow et al., “Animal Remnant Kidney Model of Chronic Renal Failure Revisited,” Hong Kong J. Nephrology, 5(2): 57-64 (2003).
Klahr, S., “The bone morphogenetic proteins (BMPs). Their role in renal fibrosis and renal function,” J. Nephrology, 16(2): 179-185 (2003).
Li, Tingting, et al., “Bone morphogenetic protein 7: a novel treatment for chronic renal and bone disease,” Curr. Opin. Nephrol. Hypertens., 13(4): 417-422 (2004).
Scott et al., “Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis,” Develop. Biol., 213(2): 283-300 (1999).
Turtle et al., “Inhibition of procollagen C-proteinase: Fibrosis and beyond,” Expert Opin. Ther. Patents, 14(8): 1185-1197 (2004) .
Klahr et al., “New approaches to delay the progression of chronic renal failure,” Kidney Int. Suppl., vol. 61, Supplement 80, pp. S23-S26 (2002).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

BMP-1 procollagen c-proteinase for diagnosis and treatment... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with BMP-1 procollagen c-proteinase for diagnosis and treatment..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and BMP-1 procollagen c-proteinase for diagnosis and treatment... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4229683

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.