Blood-viscosity reducing agent

Details Blood-viscosity reducing agent Blood-viscosity reducing agent

2011-07-05

2011-07-05

Tate, Christopher R. (Department: 1651)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

C435S002000, C435S222000, C424S780000

Reexamination Certificate

active

07972835

ABSTRACT:
A blood-viscosity reducing agent contains a protein derived fromBacillus subtilisnatto and including, sequentially from an amino group terminal, a first structural amino acid sequence having alanine, threonine, aspartic acid, glycine, valine, glutamic acid, tryptophan, asparagine, valine, aspartic acid, glutamine, isoleucine, aspartic acid, alanine, proline, lysine, alanine, tryptophan, alanine, leucine, glycine, tyrosine aspartic, acid, glycine, threonine, glycine, threonine, valine, valine, alanine, serine, isoleucine, aspartic acid, threonine, glycine, valine, glutamic acid, tryptophan, asparagine, histidine, proline, alanine, leucine, lysine, glutamic acid, lysine, tyrosine, arginine, glycine, tyrosine, asparagine, proline, glutamic acid, asparagine, proline, asparagine, glutamic acid, proline, glutamic acid, asparagine, glutamic acid, methionine, asparagine, tryptophan, tyrosine, aspartic acid, alanine, valine, alanine, glycine, glutamic acid, alanine, serine, proline, tyrosine, aspartic acid, aspartic acid, leucine, alanine, histidine, glycine, threonine, histidine, valine, and threonine, a second structural amino acid sequence having alanine, phenylalanine, serine, glutamic acid, aspartic acid, glycine, glycine, threonine, aspartic acid, alanine, aspartic acid, isoleucine, leucine, glutamic acid, alanine, glycine, glutamic acid, tryptophan, valine, and leucine, a third structural amino acid sequence having aspartic acid, alanine, glutamic acid, glycine, asparagine, proline, histidine, proline, glutamic acid, methionine, alanine, proline, aspartic acid, and valine, and a fourth structural amino acid sequence having valine, proline, glycine, glutamine, alanine, tyrosine, glutamic acid, aspartic acid, glycine, tryptophan, and aspartic acid, thereby reducing the viscosity of whole blood.

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