Blood substitutes

Details Blood substitutes Blood substitutes

1988-05-16

1991-07-02

Stone, Jacqueline

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514832, 514833, 530385, A61K 3714, C07K 1300

Patent

active

050285882

ABSTRACT:
Solutions of mutant hemoglobins having a lower oxygen affinity than that of native hemoglobin are used as blood substitutes. The mutant hemoglobins are preferably obtained by recombinant DNA techniques. Both alpha and beta globin chains can now be so prepared, making possible the production of wholly artificial hemoglobin, whether conventional or mutant in form. Solutions of wholly artificial hemoglobins are also used as blood substitutes.

REFERENCES:
patent: 4529719 (1985-07-01), Tye
Nagai et al., PNAS U.S.A., vol. 82, pp. 7252-7255, (Nov. 1985).
Nagai et al., Nature, vol. 309, (Jun. 28, 1984), pp. 810-812.
Charnay et al., Cell, vol. 38, (Aug. 1984), pp. 251-263.
Liebhaber et al., PNAS U.S.A., vol. 77, No. 12, pp. 7054-7058 (Dec. 1980).
Lau et al., Biol. Abstracts vol. 79(1), (1984), 3755.

Affiliated with

Also associated with

Rating

Blood substitutes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Blood substitutes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Blood substitutes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1247245