Blood purification means

Details Blood purification means Blood purification means

1974-12-26

1976-06-15

Spear, Jr., Frank A.

Liquid purification or separation

Recirculation

Serially connected distinct treating or storage units

128214R, 210321A, 210321B, B01D 3100

Patent

active

039636135

ABSTRACT:
A blood purification means whereby blood of a patient to be treated is led around an external circuit connecting to the patient's blood stream and is brought into direct or indirect contact with a fumarate solution, and is further brought into direct or indirect contact with an enzymic preparation, which is suitably an aspartase preparation, which catalyzes a reaction of L-aspartic acid formation from fumaric acid and ammonia. The purification means may further include a preliminary stage or stages whereat an unrequired substance in a patient's blood is decomposed to a non toxic substance and ammonia subsequently convertable to aspartic acid, and may also include a low molecular sieve means preventing re-entry of aspartic acid produced into the patient's blood stream.

REFERENCES:
patent: 3619423 (1971-11-01), Galletti et al.
patent: 3727612 (1973-04-01), Sayers et al.
patent: 3791926 (1974-02-01), Chibata et al.
patent: 3794584 (1974-02-01), Kunin
patent: 3809613 (1974-05-01), Vieth et al.
patent: 3839200 (1974-10-01), Gigou et al.
patent: 3865726 (1975-02-01), Chibata et al.

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