Blood product, a method of producing the same and a method of de

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 2, 435236, 424530, 514 8, A61K 3514, C12N 704

Patent

active

058640169

ABSTRACT:
A blood product, exclusive of albumin, inactivated relative to infectious agents, the blood product conforming to a total virus reduction factor of at least 40, having a biological acitity of at least 50%, based on its activity prior to effecting inactivation of the infectious agents, the blood product being producible from conventional blood products and being virus-safe.

REFERENCES:
patent: 4160025 (1979-07-01), Eibl et al.
patent: 4297344 (1981-10-01), Schwinn et al.
patent: 4314997 (1982-02-01), Shanbrom
patent: 4315919 (1982-02-01), Shanbrom
patent: 4379085 (1983-04-01), Williams
patent: 4404187 (1983-09-01), Schwinn et al.
patent: 4405603 (1983-09-01), Schwinn et al.
patent: 4480029 (1984-10-01), Dolana
patent: 4481189 (1984-11-01), Prince
patent: 4640834 (1987-02-01), Eibl et al.
patent: 4814435 (1989-03-01), Schwarz et al.
patent: 4904641 (1990-02-01), Eibl et al.
patent: 4909251 (1990-03-01), Seelich
patent: 4946648 (1990-08-01), Dichtelmuller et al.
patent: 5118794 (1992-06-01), Grangeorge et al.
patent: 5143838 (1992-09-01), Kraus et al.
patent: 5186945 (1993-02-01), Shanbrom
patent: 5300433 (1994-04-01), Hrinda et al.
patent: 5376633 (1994-12-01), Lezdey et al.
patent: 5418130 (1995-05-01), Platz et al.
Brummelhuis, "Preparation of the Prothrombin Complex", Methods of Plasma Protein Fractionation, pp. 117-125 (1980).
Mannucci, "Outbreak of Hepatitis A Among Italian Patients with Haemophilia", The Lancet, vol. 339, p. 819 (Mar. 28, 1992).
Pape et al., "Standardization of an in vitro Red Blood Cell Test for Evaluating the Acute Cytotoxic Potential of Tensides", Arzneim.-Forsch./Drug Res. 40, pp. 498-502 (1990).
Vogelaar et al., "Contributions to the Optimal Use of Human Blood", Vox Sanguinis, vol. 26, (1974).
Mannucci et al., "Low Risk of Viral Infection After Administration of Vapor-Heated Factor VIII Concentrate", Transfusion, vol. 32, pp. 134-138 (1992).
Muller, W., "New Ion Exchangers for the Chromatography of Biopolymers", Journal of Chromatography, 510, pp. 133-140 (1990).
E.F. Vogelaar, "Contributions to the Optimal Use of Human Blood", 1974, vol. 26, pp. 118-127.
Hellmut Hartert, "Thrombosis and Bleeding Disorders", 1971, pp. 70-76.
T. Seelich, "Side Effects of Therapy with Clotting Factor Concentrates", 1980, pp. 199-208.
H. Suomela "Preparation and Properties of a Therapeutic Factor IX Concentrate", 1977, Vox Sanguinis, Journal of Blood Transfusion, Immunohaemotology and Immunopathology, vol. 33, pp. 37-50.
Ralph Clemens, Wie Virussicher Sind Blut Und Plasmaderivate?, Z. Allg. Med. 65, 429-433 (1989) pp. 429-433.
Commission of European Communities,"AD HOC Working Party on Biotechnology/Pharmacy" 111/8115/89-EN Final, pp. 1-15, 1989.
D.B. Rubinstein, M.D., Inability of Solvent-Detergent (S-D) Treated Factor VIII Concentrate to Inactivate Parvoviruses and Non-Lipid Enveloped Non-A, Non-B Hepatitis Virus in Factor VIII Concentrate: Advantages to Using Sterlizing 100 C Dry Heat Treatment. 1990.
A.M. Prince, The Development of Virus-Free Labile Blood Derivatives. Eui. J.Epidemiol, Jun. pp. 103-118.
Chemical Abstracts, vol. 111, Nov. 27, 1989, No. 22, 201439j.
Chemical Abstracts, vol. 114, Feb. 4, 1991, No. 5, 39082a.
Rozenberg, XII International Congress on Blood Transfusion Abstracts, Aug. 17-23, 1969, Moscow, pp. 473-475.
"The Inactivation of Viruses," Chap. 3, pp. 63-65.
Epstein, J.S., et al., "Arch. Pathol. Lab Med.," vol. 114, Mar. 1990, pp. 335-340.
Levings, R.L., "Veterinary Microbiology." vol. 9, 1984, pp. 313-328.
Morgenthaler, J.J.(ed.); Curr. Stnd. Hematol. Blood Transfus. Basel, Karger; Virus Inactivation in Plasma Products, No. 56, 1989, pp. 23-33. Heimburger, N., et al.
Rubinstein, A.I.; et al.; Vox Sang, vol. 60(1), Jan. 1991, p. 60.
Meng, Z., et al; Applied and Environmental Microbiology, vol. 53(4), Apr. 1987, pp. 727-730.
Horowitz, B., et al; Transfusion, vol. 25(6), Nov.-Dec. 1985, pp. 516-522.
Piet, M.P.J, et al.; Transfusion, vol. 30(6), Jul./Aug. 1990, pp. 591-598.
Piszkiewicz, D., et al; Thrombosis Research, vol. 55(5), Sep. 1, 1989, pp. 627-634.
Chemical Abstracts, vol. 84, No. 16, Apr. 19, 1976, US Abstract No. 111640n Dec. 25, 1975.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Blood product, a method of producing the same and a method of de does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Blood product, a method of producing the same and a method of de, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Blood product, a method of producing the same and a method of de will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1451324

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.