Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1992-07-02
1993-06-15
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
A61K 3150
Patent
active
052198545
ABSTRACT:
A blood platelet-decreasing therapeutic drug comprising as an effective ingredient a 3(2H)-pyridazinone compound of the formula (I): ##STR1## wherein each of R.sup.1 and R.sup.2, which are independent of each other, is a hydrogen atom or a C.sub.1-4 alkyl group, and X is a chlorine atom or a bromine atom, or a pharmaceutically acceptable salt thereof.
REFERENCES:
patent: 4892947 (1990-01-01), Mutsukado et al.
patent: 4978665 (1990-12-01), Tanikawa et al.
Japanese Journal of Pharmacology, vol. 56, No. 1, May 1992, pp. 79-84, A. Yamamoto, et al., "Effects of NZ-107 on Tracheal Responses to Adenosine in the Guinea Pig".
Japanese Journal of Pharmacology, vol. 43, No. 2, Feb. 1991, pp. 83-87, A. Yamamoto, et al., "Effect of an Anti-SRS-A Agent, NZ-107, on Airway Responses Induced by Ovalbumin and A23187 in the Guinea-Pig".
Kikuchi Nobuyuki
Miyamoto Misao
Nakashima Mitsuyoshi
Jarvis William
Nissan Chemical Industries Ltd.
Waddell Frederick E.
Zeria Pharmaceutical Co. Ltd.
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