Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...
Patent
1987-05-08
1991-07-23
Spear, Frank
Liquid purification or separation
Processes
Liquid/liquid solvent or colloidal extraction or diffusing...
21032168, B01D 6118
Patent
active
050341359
ABSTRACT:
A system for separating at least one constituent from a liquid suspension such as blood induces high velocity flow by viscous drag about the circumference of a spinner having a filtration membrane with pore size selected for the desired constituent. The high velocity circumferential flow is bounded by a spaced apart shear wall, with a spacing selected relative to the diameter of the spinner and its rotational velocity, also with respect to the viscosity of the suspension, to establish a flow within the shear gap, as substantial centrifugal forces are exerted upon the suspension. Under these conditions, filtrate in contact with the membrane is replenished, and filtrate passes through the membrane with minimal adverse effects from deposition and concentration polarization, and with high efficiency because of high shear levels that are maintained. The filtrate is collected within the interior of the spinner in a conduit system and passed to an outlet orifice.
REFERENCES:
patent: Re31688 (1984-09-01), Popovich et al.
patent: 1664769 (1928-04-01), Chance
patent: 2197509 (1940-04-01), Reilly et al.
patent: 2398233 (1946-04-01), Lincoln
patent: 2670849 (1954-03-01), Dunmire
patent: 2709500 (1955-05-01), Carter
patent: 3026871 (1962-03-01), Thomas
patent: 3183908 (1965-05-01), Collings
patent: 3355382 (1967-11-01), Huntington
patent: 3396103 (1968-06-01), Huntington
patent: 3491887 (1970-01-01), Maestrelli
patent: 3523568 (1970-08-01), Van Leeuwen
patent: 3568835 (1971-03-01), Hansen
patent: 3634228 (1972-01-01), Latham, Jr.
patent: 3647632 (1972-03-01), Johnson et al.
patent: 3674440 (1972-07-01), Kitrilakis
patent: 3705100 (1972-12-01), Blatt et al.
patent: 3771658 (1973-11-01), Brumfield
patent: 3771899 (1973-11-01), Brumfield
patent: 3821108 (1974-06-01), Manjikian
patent: 3830372 (1974-11-01), Manjikian
patent: 3847817 (1974-05-01), Jarman
patent: 3883434 (1975-05-01), Gayler
patent: 3900398 (1975-04-01), Gillette
patent: 3977976 (1976-12-01), Spaan et al.
patent: 4040965 (1977-08-01), Kohlhes
patent: 4062771 (1977-12-01), Saupe
patent: 4066554 (1978-02-01), Guyer
patent: 4093552 (1978-06-01), Guyer
patent: 4184952 (1980-01-01), Stewart
patent: 4191182 (1980-03-01), Popovich et al.
patent: 4212741 (1980-07-01), Brumfield
patent: 4212742 (1980-07-01), Solomon et al.
patent: 4535062 (1985-08-01), Muller
Smeby, "The Taylor-Vortex Membrane Oxygenator", Stratchchyde Bioengineering Seminars, Artificial Organs, University Park Press, R. M. Kenedi (Editor), pp. 70-82.
Colton, "Fundamentals of Gas Transport in Blood", Artificial Lungs for Acute Respiratory Failure-Theory and Practice, Zapol and Qvist (Editors), Academic Press, N.Y., pp. 3-41 (1976).
Kitrilakis et al., "A Rotary Disk Membrane Oxygenator", Artificial Lungs for Acute Respiratory Failure-Theory and Practice, Zapol and Qvist (Editors), Academic Press, N.Y., pp. 211-221 (1976).
Kozinski et al., "Protein Ultrafiltration: A General Example of Boundary Layer Filtration", AlChE Journal (vol. 18, No. 5) Sep. 1972, pp. 1030-1040.
A. K. Bhagat/C. R. Wilke, "Filtration Studies with Ultrafine Particles", 9/66, University of California, Lawrence Radiation Laboratory, Berkeley, CA, UCRL-16574, preprint released for announcement in Nuclear Science Abstracts.
A. K. Bhagat and C. R. Wilke, "Engineering Analysis Of The Rotorfermentor", Aug. 1971, paper presented at the annual meeting of the Society for Industrial Microbiology, Aug. 29-Sep. 4, 1971, Colorado State University, Fort Collins, Colorado.
W. Tobler, "Dynamic Filtration-The Engineering Concept of the Escher Wyss Pressure Filter," Nov./Dec. 1979, Filtration and Separation, pp. 630-632.
Miguel Lopez-Leiva, Ph.D. Dissertation, "Ultrafiltration in Rotary Annular Flow", Dec. 1979, Division of Food Engineering, Lund University, Sweden.
W. Tobler, "Dynamic Filtration: Principle and Application of Shear Filtration in an Annular Gap," Filtration and Separation Jul./Aug. 1982, pp. 329-333.
"Hydrodynamics of Annular Gap Flow Between Permeable Cylinder Walls" Escher Wyss Mitteilungen 2/1978-1/1979, 24-30; J. Lieberherr.
A. Werynski et al., "Membrane Plasma Separation: Toward Improved Clinical Operation," Trans. Am. Soc. Artificial Internal Organs, vol. XXVII (1981) pp. 539-543.
K. Schindhelm et al., "Mass Transfer Characteristics of Plasma Filtration Membranes," Trans. Am. Soc. Artificial Internal Organs, vol. XXVII (1981) pp. 554-558.
Int. Appl. WO82/03567, published 10-1982.
Formed Element Deposition onto Filtering Walls, R. J. Forstrom et al., Trans. Amer. Soc. Artif. Internal Organs 21:602 (1974).
The Filtration of Plasma from Whole Blood: A Novel Approach to Clinical Detoxification, F. Castino et al. in : Chang TMS ed. Artificial Kidney, Artificial Liver, and Artificial Cells, New York: Plenum Press.
Continuous Flow Membrane Filtration of Plasma from Whole Blood, B. A. Solomon et al., Trans. Amer. Soc. Arfif. Internal Organs 24:21 (1978).
Filtration Plasmapheresis in Vivo, T. B. Wittbans et al., Transfusion, vol. 21, No. 5, pp. 502-510.
Membrane Separations: Technological Principals and Issues, B. A. Solomon, Trans. Am. Soc. Artif. Internal Organs (1981) pp. 345-350.
Continuous Flow Membrane Plasmapheresis: Theoretical Modes for Flux and Hemolysis Prediction, A. L. Zydney et al., Trans. Am. Soc. Artif. Internal Organs pp. 408-412 (1982).
Stability of a Viscous Liquid Contained Between Rotating Cylinders, G. I. Taylor, Phil. Trans. Roy. Soc.: A 223:289 (1923).
Distribution of Velocity and Temperature Between Concentric Rotating Cylinders, G. I. Taylor, Phil. Trans. Roy. Soc.: A 151:494 (1932).
Boundary-Layer Theory, H. Schlichting, pp. 500-509, 521-522, McGraw-Hill, N.Y. (1968).
How Does Fluid Flow Become Turbulant, Arthur L. Robinson, Science, 221:140, Jul. 1983.
Gas Transfer and Thrombogenesis in an Annular Membrane Oxygenator with Active Blood Mixing, J. D. S. Gaylor et al., vol. XIX Trans. American Soc. Artif. Internal Organs, 1973, pp. 516-524.
N. S. Thesis of Teddy William Wood in Deposition of Red Blood Cells onto Filtering Surfaces-Univ. of Minnesota, 1914.
An Experimental Study of Mass Transfer in Rotating Conette Flow with Low Axial Reynolds Number, A. B. Strong et al., The Canadian Journal of Chemical Engineering, vol. 54, Aug. 1976, pp. 295-298.
Self-Diffusion of Particles in Shear Flow of a Suspension, E. C. Eckstein et al., J. Fluid Mech (1970 vol. 79, part a, pp. 191-208, Filtration Studies with Ultrafine Particles, C. R. Wilke et al.
University of California UCRL-16574 Sep. 1966, p. 106.
Desalination by Reverse Osmosis, T. K. Sherwood et al., Fundamentals, vol. 6, No. 1, Feb. 1967, pp. 2-12.
Description of a Rotating Ultrafiltration Module, B. Hallstrom and M. Lopez-Leiva, Desalination, Netherlands 24 (1978), 273-279.
Ultrafiltration at Low Degrees of Concentration Polarization: Technical Possibilities, M. Lopez-Leiva, Desalination, Netherlands (1980).
Cross Flow Filtration and Axial Filtration, K. A. Kraus (unknown origin and date) pp. 1059-1075.
McLaughlin William F.
Spear Frank
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