Blood control standard

Details Blood control standard Blood control standard

1977-11-22

1978-11-21

Padgett, Benjamin R.

Compositions

Nonreactive analytical, testing, or indicating compositions

23230B, 424 2, 424 3, G01N 3316

Patent

active

041265750

ABSTRACT:
A stable blood control standard for the quality control of the measurement of blood pH and gases in the clinical laboratory and method of making the same is disclosed. The blood control standard comprises a sealed receptacle containing specially treated red cells and a gaseous head space at least equal to about the volume of the red cells. The special treatment comprises thoroughly washing and separating the red cells from the plasma components and followed by mildly treating the cells with aldehyde and retaining the cells in a buffered solution. The special treatment also includes treating at least a portion of the red cells with carbon monoxide. The head space comprises from 0-15% CO.sub.2, 0-25% O.sub.2 and the balance N.sub.2 and/or inert gas.

REFERENCES:
patent: 3681255 (1972-08-01), Wilfore
patent: 3859049 (1975-01-01), Ware et al.
patent: 3879510 (1975-04-01), Kitajima et al.
patent: 3973913 (1976-08-01), Louderback
patent: 3977995 (1976-08-01), Louderback et al.
patent: 4001142 (1977-01-01), Turner
patent: 4027971 (1977-06-01), Kolman et al.
Henry, R. J., Clinical Chemistry Principles and Technics, Hoeber Medical Div., Harper & Row, Publ., pp. 731-741, 748-749 (1964).

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