Blood compatible polymers for blood oxygenation devices

Details Blood compatible polymers for blood oxygenation devices Blood compatible polymers for blood oxygenation devices

1974-12-26

1977-02-15

Wolk, Morris O.

Chemistry: physical processes

Physical processes

Crystallization

210321B, 210500M, 128DIG3, A61M 103, B01D 3918

Patent

active

040080471

ABSTRACT:
Fluoroacylation of ethyl cellulose has been found to result in good gas permeability and blood compatibility for polymeric layers made from the resulting fluorinated esters. The fluoroacylated ethyl cellulose has good hydrolytic stability at blood pH and under sterilization conditions (e.g. 100.degree. C). For use in blood oxygenation devices, implantable biomedical devices, blood sampling or analysis or purification devices, etc., it is preferred that the fluoroacylated ethyl cellulose be substantially free of residual OH and have a fluorine content above 10% by weight (e.g. at least about 12% by weight).

REFERENCES:
patent: 2980491 (1961-04-01), Metairie et al.
patent: 3551244 (1970-12-01), Forester et al.
patent: 3592672 (1971-07-01), Rowley et al.
patent: 3592953 (1971-07-01), Ward et al.
patent: 3839743 (1974-10-01), Schwarcz
patent: 3865615 (1975-02-01), Manly
patent: 3878109 (1975-04-01), Ikeda et al.
"Interactions of Materials with Blood", Ch. 3, pp. 73-118, Blood Compatible Synthetic Polymers, Bruck, 1974.

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