Blood-compatible material of a supramolecular structure

Details Blood-compatible material of a supramolecular structure Blood-compatible material of a supramolecular structure

1998-04-29

2000-03-14

Szekely, Peter A.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Processes of preparing a desired or intentional composition...

424 7838, 424488, 424529, 424425, 514 58, 5147723, 524 48, A01N 100, A61K 31765, A61K 4736, C08L 516

Patent

active

060373873

ABSTRACT:
A platelet metabolism suppressing blood compatible material has a supramolecular structure containing a plurality of cyclic compounds and a hydrophilic straight-chain polymer threading into cavities of the cyclic compounds. Both terminals of the polymer are respectively capped with biodegradable groups having bulks sufficient to prevent the dethreading of the cyclic compounds.

REFERENCES:
patent: 4927636 (1990-05-01), Hijiya et al.
patent: 5384186 (1995-01-01), Trinh
patent: 5855900 (1999-01-01), Nobuhiko
Wataru Kamimura, et al., Journal of Controlled Release, vol. 44, No. 2/03, pp. 295 to 299, "Interaction of Supramolecular Assembly with Hairless Rat Stratum Corneum", Feb. 17, 1997.
Shoji Nagaoka, et al., Biomaterials, vol. 11, No. 2, pp. 119 to 121, "Clinical Application of Antithrombogenic Hydrogel with Long Poly(ethylen oxide) Chains", Mar. 1990.

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