Blood compatible, lubricious article and composition and method

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514822, 604265, 427 2, A61K 3514

Patent

active

050137174

ABSTRACT:
A leach resistant composition includes a quaternary ammonium complex of heparin and a silicone. A method for applying a coating of the composition to a surface of a medical article is within the purview of the present invention. Medical articles having surfaces which are both lubricious and antithrombogenic, are produced in accordance with the method hereof.

REFERENCES:
patent: 4326532 (1982-04-01), Hammar
patent: 4529614 (1985-07-01), Burns
patent: 4676975 (1987-06-01), McGary et al.
patent: 4678468 (1987-07-01), Hiroyoshi
patent: 4720521 (1988-01-01), Spielvogel et al.
patent: 4925668 (1990-05-01), Khan et al.
Dow Corning 360 Medical Fluid, Product Bulletin: 51-374B, May 1982, Dow Corning Corporation, Midland, Mich.
Petrarch Systems, Bristol, Pa., Conventional Silicone Fluids.

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